Team "Integrative Multimodal Imaging in Healthcare"
Laura Harsan
email: harsan[at]unistra.fr
The team’s project aims to identify and validate new biomarkers using MRI imaging and metabolomics to better understand, predict, diagnose and treat age-related neurological disorders (such as Alzheimer’s disease and Lewy body dementia), psychiatric disorders (depression, catatonic disorders), neurocognitive eating disorders (childhood obesity) and certain oncological conditions. It is divided into three areas: (1) metabolic phenotyping and characterisation of tumoural brain tissue for neurosurgery, (2) study of brain connectivity for developmental neurology, ageing and psychiatry, (3) development of quantitative multi-modal imaging for preclinical mouse models. This project combines research on small animals with translational studies between mouse and human models, enabling an interdisciplinary approach across neurology, neuroscience, radiology and biophysics, and facilitating the rapid transfer of knowledge from preclinical research to clinical practice and vice versa.
Research areas: Brain connectivity imaging ; Preclinical multimodal imaging ; Neural bases ; Biomarkers & therapies for neurogeriatric and psychogeriatric diseases.
Techniques: Imaging (MRI, MRS, PET) ; Connectivity study (ICA, BOLD…)& modulation (rTMS).
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