Publications

Dunod edition 

Médecine de la douleur: mécanismes physiologiques et pathologiques de la douleur et de l’analgésie

^{Sous la direction de P Poisbeau et M Melchior}

Bio Cell.

The different cellular entry routes for drug delivery using cell penetrating peptides

^{Okafor M, Schmitt D, Ory S, Gasman S, Hureau C, Faller P, Vitale N}

Journal of Proteome Research

Mind Your Spectra: Points to be Aware of When Validating the Identification of Isobaric Histone Peptidoforms

^{Hijazi H, Manessier J, Brugiere S, Ravnsborg T, Courçon M, Brule B, Merienne K, Jensen ON, Hesse AM, Bruley C, Pflieger D}

Frontiers in Neuroscience

Planarian RNAi knockdown: feeding once might just be enough

^{Reho G, Menger Y, Cadiou H}

The Journal of Neuroscience

Calretinin-Expressing Neurons in the Basal Forebrain Specifically Contact Granule Cells in the Olfactory Bulb and Modulate Odor Learning

^{Constantinescu, V. S., Folschweiller, S., Siri, T., Alonso, M., De Saint Jan, D., & Saghatelyan, A}

EBioMedicine

Using multiomic integration to improve blood biomarkers of major depressive disorder: a case-control study

^{Mokhtari A, Ibrahim EC, Gloaguen A, Barrot CC, Cohen D,Derouin M, Vachon H, Charbonnier G, Loriod B, Decraene C, Yalcin I, Marie-Claire C, Etain B, Belzeaux R, Delahaye-Duriez A, Lutz PE}

Journal of lipid research

Cholesterol affects the binding of proteins to phosphatidic acid without influencing its ionization properties

^{Desmond Owusu Kwarteng, Alexander Wolf, Madisyn Langdon, Nawal Kassas, Nicolas Vitale, and Edgar Eduard Kooijman}

Glia

Hippocampal Astrocyte Morphology Follows an Unexpected Trajectory With Age in a Transgenic Rodent Model of Tauopathy

^{Augustin E, Vinasco-Sandoval T, Riquelme-Perez M, Plassard D, Gaudin M, Aurégan G, Mitja J, Bernier S, Joséphine C, Petit F, Jan C, Hérard AS, Gaillard MC, Launay A, Faivre E, Buée L, Boutillier AL, Blum D, Bemelmans AP, Bonvento G, Cambon K}

Nature Communications 

Accelerated epigenetic aging in Huntington's disease involves polycomb repressive complex 1

^{Brulé B, Alcalá-Vida R, Penaud N, Scuto J, Mounier C,Seguin J,Khodaverdian SV, Cosquer B, Birmelé E, Le Gras S, Decraene C, Boutillier AL, Merienne K}

Brain

Loss of the neuronal kinase DCLK3 leads to anxiety-like behaviour and memory deficits

^{de Longprez L, Gaillard MC, Decraene C, Perot JB, Keime C, Nadkarni N, Louça M, Jan C, Liot G, Aurégan G, Guillermier M, Mitja J, Hantraye P, Bertaux F, Norbert M, Bonvento G, Flament J, Dhenain M, Neri C, Bemelmans AP, Mérienne K, Cambon K, Brouillet E}

International Journal of Molecular sciences

Binge Eating and Obesity Differentially Alter the Mesolimbic Endocannabinoid System in Rats

^{Schoukroun F, Herbeaux K, Andry V, Goumon Y, Bourdy R,  Befort K}

The Journal of Physiology

Impaired oxytocin signaling in the central amygdala in rats with chronic heart failure

_{Althammer F, Roy R, Kirchner M, Campos-Lira E, Schimmer S, Charlet A, Grinevich V, Stern J}

Neurobiology of Disease

A novel mouse model reproducing frontal alterations related to the prodromal stage of dementia with LEWY bodies

^{Schueller E, Grgurina I, Cosquer B, Panzer E, Penaud N, Pereira de Vasconcelos A, Stéphan A, Merienne K, Cassel JC, Mathis C, Blanc F, Bousiges O, Boutillier AL}

BioRxiv

Next-generation Cu(II) selective peptide shuttles prevent Cu(Aβ)-induced toxicity and microglial activation in organotypic hippocampal slices

^{Okafor M, Schmitt D, Gasman S, Raibaut L, Hureau C, Faller P, Vitale N}

Neurobiology of Disease

Dysregulated expression of cholesterol biosynthetic genes in Alzheimer's disease alters epigenomic signatures of hippocampal neurons

^{Paiva I, Seguin J, Grgurina I, Singh AK, Cosquer B, Plassard D, Tzeplaeff L, Le Gras S, Cotellessa L, Decraene C, Gambi J, Alcala-Vida R, Eswaramoorthy M, Buée L, Cassel JC, Giacobini P, Blum D, Merienne K, Kundu TK, Boutillier AL}

 J Neurosci

Phospholipid Scramblase 1 Controls Efficient Neurotransmission and Synaptic Vesicle Retrieval at Cerebellar Synapses

^{Caputo M, Ivanova D, Chasserot-Golaz S, Doussau F, Haeberlé AM, Royer C, Ozkan S, Ecard J, Bader MF, Vitale N, Cousin MA, Tóth P, Gasman S, Ory P}

Brain

Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice

^{Gomez-Murcia V, Launay A, Carvalho K, Burgard A,Meriaux C, Caillierez R, Eddarkaoui S, Kilinc D, Siedlecki-Wullich D, Besegher M, Bégard S, Thiroux B, Jung M, Nebie O, Wisztorski M, Déglon N, Montmasson C, Bemelmans AP, Hamdane M, Lebouvier T, Vieau D, Fournier I, Buee L, Lévi S, Lopes LV, Boutillier AL, Faivre E, Blum D}

Journal of Neuroscience Methods

Disconnecting prefrontal cortical neurons from the ventral midline thalamus: Loss of specificity due to progressive neural toxicity of an AAV-Cre in the rat thalamus

^{Panzer E, Boch L, Cosquer B, Grgurina I, Boutillier AL, de Vasconcelos AP, Stephan A, Cassel JC}

Front Mol Biosci

Restoring cellular copper homeostasis in Alzheimer disease: a novel peptide shuttle is internalized by an ATP-dependent endocytosis pathway involving Rab5- and Rab14-endosomes

^{Okafor M, Champomier O, Raibaut L, Ozkan S, El Kholti N, Ory S, Chasserot-Golaz S, Gasman S, Hureau C, Faller P, Vitale N}

Neuropsychopharmacology

The rostromedial tegmental nucleus gates fat overconsumption through ventral tegmental area output

^{Schoukroun F, Befort K, Bourdy R}

GeroScience

Intermittent working memory training during adulthood protects against age-related long-term spatial reference memory decline in rats

^{Barbelivien A, Durieux L, Seys E, Majchrzak M}

Nutrition Neuroscience

Altered reward processing following sucrose bingeing in male and female mice

^{Awad G, Aubry AS, Olmstead MC, Befort K}

EMBO J

DDHD2-STXBP1 interaction mediates long-term memory via the generation of saturated free fatty acids

^{Akefe IO, Saber SH, Matthews B, Venkatesh BG, Gormal RS, Blackmore DG, Sieriecki E, Gambin Y, Bertran-Gonzalez J, Vitale N, Humeau Y, Michaels AA, Xue M, Cravatt B, Joensuu M, Wallis TM & Meunier FA}

Behavioural Brain Research

Behavioural characteristics and sex differences of a treatment-resistant depression model: chronic mild stress in the Wistar-Kyoto rat

^{Loizeau V, Durieux L, Mendoza J, Wiborg O, Barbelivien A, Lecourtier L}

MedSci

Sécrétion hormonale des phéochromocytomes. Une dangeureuse histoire d’exocytose mal controlée

^{Streit L, Tanguy E, Brunaud L, Toth P, Vitale N, Ory S and Gasman S}

The Journal of Neuroscience

Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting

 _{Barnett D, Bohmbach K, Grelot V, Charlet A, Dallérac G, Ju Y H, Nagai J and Orr A G}

Cellular and Molecular Life Sciences

Chromogranin A and its derived peptides: potential regulators of cholesterol homeostasis

^{Dhanya R Iyer, Venkatraman J, Tanguy E, Vitale N and Mahapatra NR}

Progress in Neurobiology

Mutant FUS induces chromatin reorganization in the hippocampus and alters memory processes

^{Tzeplaeff L, Seguin J, Le Gras S, Megat S, Cosquer B, Plassard D, Dieterlé S, Paiva I, Picchiarelli G, Decraene C, Alcala-Vida R, Cassel JC, Merienne K, Dupuis L, Boutillier AL}

Nature Metabolism

CaMK1D signalling in AgRP neurons promotes ghrelin-mediated food intake

_{Vivot K, Meszaros G, Zhang Z, Erbs E, Yeghiazaryan G, Quinones M, Grandgirard E, Schneider A, Clauss--Creusot E, Charlet A, Faour M, Martin C, Luquet S, Kloppenburg P, Nogueiras R, Ricci R}

International Journal of Molecular sciences

The role of the endocannabinoid system in binge eating

^{Bourdy R, Befort K}

Front Mol Biosci

V-ATPase modulates exocytosis in neuroendocrine cells through the activation of an ARNO-Arf6-PLD pathway and the synthesis of phosphatidic acid

^{Wang Q, Wolf A, Ozkan S., Richert L, Mely Y, Chasserot-Golaz S, Ory S, Gasman S, and Vitale N}

 Nature Communications

Optical control of PIEZO1 channels

^{Peralta FA, Balcon M, Martz A, Biljali D, Cevoli F, Arnould B, Taly A, Chataigneau T, & Grutter T}

Neuroscience Letters

Circadian functioning of Locus Cœruleus of the nocturnal rat and diurnal rodent Arvicanthis

^{Caputo R, Poirel VJ, Paiva I, Boutillier AL, Challet E, Meijer JH, Raison S}

Nature communications

 An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats

_{Iwasaki M, Lefevre A, Althammer F, Clauss Creusot E, Lapies O, Petitjean H, Hilfiger L, Kerspern D, Melchior M, Küppers S, Krablicher Q, Patwell R, Kania A, Gruber T, Kirchner MK, Wimmer M, Frohlich H, Dotsch L, Schimmer J, Herpertz SC, Ditzen B, Schaaf CP, Schoenig K, Bartsch D, Gugula A, Trenk A, Blasiak A, Stern JE, Darbon P, Grinevich V, Charlet A}

Cells

A Role for the V0 Sector of the V-ATPase in Neuroexocytosis: Exogenous V0d Blocks Complexin and SNARE Interactions with V0c

^{Lévêque C, Maulet Y, Wang Q, Rame M, Rodriguez L, Mochida S, Sangiardi M, Youssouf F, Iborra C, Seagar M, Vitale N, El Far O}

Adv Biol Regul.

Phospholipase D and cancer metastasis: A focus on exosomes

^{Wolf A, Tanguy E., Wang Q, Gasman S, Vitale N}

Cells

The Role of Oxytocin in Abnormal Brain Development: Effect on Glial Cells and Neuroinflammation

_{Knoop M, Possovre ML, Jacquens A, Charlet A, Baud O, Darbon P}

EMBO Rep.

Parkin coordinates mitochondrial lipid remodeling to execute mitophagy

^{Lin CC, Yan J, Kapur MD, Norris KL, Hsieh CW, Lai CH, Lim KL, Vitale N, Guan Z, Chi JT, Yang WY, and TP Yao}

Journal of Neuroendocrinology

Analysis of the hypothalamic oxytocin system and oxytocin receptor-expressing astrocytes in the Magel2tm1.Stw mouse model of Prader-Willi syndrome

_{Althammer F, Wimmer M, Krabichler Q, Kuppers S, Schimmer J, Frohlich H, Dotsch L, Stern JE, Charlet A, Grinevich V, Schaaf CP}

Progress in Neurobiology

Altered activity-regulated H3K9 acetylation at TGF-beta signaling genes during egocentric memory in Huntington's disease

^{Alcalá-Vida R, Lotz C, Brulé B, Seguin J,Decraene C, Awada A, Bombardier A, Cosquer B, Pereira de Vasconcelos A, Brouillet E, Cassel JC, Boutillier AL, Merienne K}

Progress in Biology

Emerging role of astrocytes in oxytocin-mediated control of neural circuits and brain functions
_{Angel Baudon, Etienne Clauss Creusot, Ferdinand Althammer, Christian P Schaaf, Alexandre Charlet}

Chem Sci

Development of Cu(ii)-specific peptide shuttles capable of preventing Cu-amyloid beta toxicity and importing bioavailable Cu into cells

^{Okafor M, Gonzalez P, Ronot P, El Masoudi I, Boos A, Ory S, Chasserot-Golaz S, Gasman S, Raibaut L, Hureau C, Vitale N, Faller P}

Science

GnRH replacement rescues cognition in Down syndrome

^{Manfredi-Lozano M, Leysen V, Adamo M, Paiva I, Rovera R, Pignat JM, Timzoura FE, Candlish M, Eddarkaoui S, Malone SA, Silva MSB, Trova S, Imbernon M, Decoster L, Cotellessa L, Tena-Sempere M, Claret M, Paoloni-Giacobino A, Plassard D, Paccou E, Vionnet N, Acierno J, Maceski AM, Lutti A, Pfrieger F, Rasika S, Santoni F, Boehm U, Ciofi P, Buée L, Haddjeri N, Boutillier AL, Kuhle J, Messina A, Draganski B, Giacobini P, Pitteloud N, Prevot V}

J Cell Biol

ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ER-mitochondria contact sites

^{Guyard V, Monteiro-Cardoso VF, Omrane M, Sauvanet C, Houcine A, Boulogne C, Ben Mbarek K, Vitale N, Faklaris O, El Khallouki N, Thiam AR, Giordano F.}

Cancer Lett.

Dysfunction of calcium-regulated exocytosis at a single-cell level causes catecholamine hypersecretion in patients with pheochromocytoma

^{Houy S, Streit L, Drissa I, Rame M, Decraene C, Moog S, Brunaud L, Lanoix J, Chelbi R, Bihain F, Lacomme S, Lomazzi S, Campoli P, Vix M, Mutter D, Paramithiotis E, Dubessy C, Vitale N, Ory S, Gasman S}

Douleur et analgésie

Neuroinflammation Induced by Uncontrolled Food Intake: Risk of Chronic Pain?

^{Aubry AS, Awad G,Befort K}

Cancers (Basel).

Management of Patients with Treatment of Pheochromocytoma: A Critical Appraisal

^{Bihain F, Nomine-Criqui C, Guerci P, Gasman S, Klein M, Brunaud L}

Frontiers in Molecular Neuroscience

TRP channels and monoterpenes: Past and current leads on analgesic properties

^{Petitjean H, Héberlé E, Hilfiger L, Łapieś O, Rodrigue G, Charlet A}

Journal of Neuroendocrinology

Altered PVN-to-CA2 hippocampal oxytocin pathway in heart failure rats

_{Althammer F, Roy R, Lefevre A, Najjar R, Bartsch D, Eliava M, Feresin R, Hammock E, Murphy AZ, Charlet A, Grinevich V, Stern JE}

The Journal of Clinical Investigation

Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription
_{Isabel Paiva, Lucrezia Cellai, Céline Meriaux, Lauranne Poncelet, Ouada Nebie, Jean-Michel Saliou, Anne-Sophie Lacoste, Anthony Papegaey, Hervé Drobecq, Stéphanie Le Gras, Marion Schneider, Enas M Malik, Christa E Müller, Emilie Faivre, Kevin Carvalho, Victoria Gomez-Murcia, Didier Vieau, Bryan Thiroux, Sabiha Eddarkaoui, Thibaud Lebouvier, Estelle Schueller, Laura Tzeplaeff, Iris Grgurina, Jonathan Seguin, Jonathan Stauber, Luisa V Lopes, Luc Buée, Valérie Buée-Scherrer, Rodrigo A Cunha, Rima Ait-Belkacem, Nicolas Sergeant, Jean-Sébastien Annicotte, Anne-Laurence Boutillier, David Blum}

Aging Brain

Early memory deficits and extensive brain network disorganization in the AppNL-F/MAPT double knock-in mouse model of familial Alzheimer's disease

^{Borcuk C, Héraud C, Herbeaux K, Diringer M, Panzer É, Scuto J, Hashimoto S, Saido TC, Saito T, Goutagny R, Battaglia D, Mathis C}

Developmental Biology

Circadian clocks, retinogenesis and ocular health in vertebrates: new molecular insights
_{Amandine Bery, Udita Bagchi, Arthur A Bergen, Marie-Paule Felder-Schmittbuhl}

Nature Reviews Psychology

The distinction between temporal order and duration processing, and implications for schizophrenia
_{Jennifer T. Coull & Anne Giersch} 

Molecular Neurobiology

Hippocampal cannabinoid 1 receptors are modulated following cocaine self-administration in male rats
_{De Sa Nogueira D, Bourdy R, Alcala-Vida R, Filliol D, Andry V, Goumon Y, Zwiller J, Romieu P, Merienne K, Olmstead MC, Befort K}

Movement Disorders

Infectious Agents as Potential Drivers of α-Synucleinopathies
_{Linard M, Ravier A, Mougué L, Grgurina I, Boutillier AL, Foubert-Samier A, Blanc F, Helmer C.}

Journal of affective disorders

An overactive mind: Investigating racing thoughts in ADHD, hypomania and comorbid ADHD and bipolar disorder via verbal fluency tasks
_{Martz E, Weibel S, Weiner L.
L'étude montre le caractère transdiagnostique de ce qu'on appelle la tachypsychie, ou l'accélération de la pensée}

Molecular Neurobiology

Hippocampal cannabinoid 1 receptors are modulated following cocaine self-administration in male rats

^{De Sa Nogueira D, Bourdy R, Alcala-Vida R, Filliol D, Andry V, Goumon Y, Zwiller J, Romieu P, Merienne K, Olmstead MC, Befort K}

STAR Protocols

Calcium imaging and BAPTA loading of amygdala astrocytes in mouse brain slices

_{Baudon A, Clauss-Creusot E, Darbon P, Patwell R, Grinevich V, Charlet A}

STAR Protocols

Identification and three-dimensional reconstruction of oxytocin receptor expressing astrocytes in the rat and mouse brain

_{Althammer F, Krause EG, de Kloet AD, Smith J, Grinevich V, Charlet A, Stern JE}

Cancer Lett. 

Somatostatin analogue pasireotide (SOM230) inhibits catecholamine secretion in human pheochromocytoma cells

^{Streit L, Moog S, Hugel S, Rame M, Tanguy E, Andry V, Schmid HA, Brunaud L, Bihain F, Nominé-Criqui C, Goumon Y, Lacomme S, Lomazzi S, Vix M, Mutter D, Vitale N, Ory S, Gasman S}

Adv Biol Regul.

Phospholipase D1-generated phosphatidic acid modulates secretory granule trafficking from biogenesis to compensatory endocytosis in neuroendocrine cells

^{Tanguy E, Wolf A, Wang Q, Chasserot-Golaz S, Ory S, Gasman S, Vitale N}

STAR Protocols

Viral vectors for opto-electrode recording and photometry-based imaging of ocytocin neurons in anaesthetized and socially interacting rats

_{Tang Y , Benusiglio D, Lefevre A, Küppers S, Lapies O, Kerspern D, Charlet A, Grinevich V}

eLife

Sushi domain-containing protein 4 controls synaptic plasticity and motor learning
_{Inés González-Calvo, Keerthana Iyer, Mélanie Carquin, Anouar Khayachi, Fernando A Giuliani, Séverine M Sigoillot, Jean Vincent, Martial Séveno, Maxime Veleanu, Sylvana Tahraoui, Mélanie Albert, Oana Vigy, Célia Bosso-Lefèvre, Yann Nadjar, Andréa Dumoulin, Antoine Triller, Jean-Louis Bessereau, Laure Rondi-Reig, Philippe Isope, Fekrije Selimi} 

Nature Neuroscience

Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents
_{Jérôme Wahis, Angel Baudon, Ferdinand Althammer, Damien Kerspern, Stéphanie Goyon, Daisuke Hagiwara, Arthur Lefevre, Lara Barteczko, Benjamin Boury-Jamot, Benjamin Bellanger, Marios Abatis, Miriam Da Silva Gouveia, Diego Benusiglio, Marina Eliava, Andrei Rozov, Ivan Weinsanto, Hanna Sophie Knobloch-Bollmann, Matthew K Kirchner, Ranjan K Roy, Hong Wang, Marie Pertin, Perrine Inquimbert, Claudia Pitzer, Jan Siemens, Yannick Goumon, Benjamin Boutrel, Christophe Maurice Lamy, Isabelle Decosterd, Jean-Yves Chatton, Nathalie Rouach, W Scott Young, Javier E Stern, Pierrick Poisbeau, Ron Stoop, Pascal Darbon, Valery Grinevich, Alexandre Charlet}

European Journal of Neuroscience

The burden of early life stress on the nociceptive system development and pain responses
_{Meggane Melchior, Pierre Kuhn, Pierrick Poisbeau}

Nature Communications

Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation
_{Pierre-Eric Lutz, Marc-Aurèle Chay, Alain Pacis, Gary G Chen, Zahia Aouabed, Elisabetta Maffioletti, Jean-François Théroux, Jean-Christophe Grenier, Jennie Yang, Maria Aguirre, Carl Ernst, Adriana Redensek, Léon C van Kempen, Ipek Yalcin, Tony Kwan, Naguib Mechawar, Tomi Pastinen}